| Gene Name | GDF11 BMP11 |
| Protein Name | GDF11 |
| Immunogen | Synthesized peptide derived from human GDF11 |
| Specificity | This antibody detects endogenous levels of GDF11 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | Rabbit |
| Dilution | WB 1：500-2000 |
| Puification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| MolecularWeight(Da) | 44770 |
| Concentration | 1 mg/ml |
| Storage | -20°C/1 year |
| Subcellular Location | extracellular region,extracellular space,nucleoplasm,intracellular membrane-bounded organelle,protein complex, |
| Background | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging. [provided by RefSeq, Aug 2016], |
| Function | function:Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern.,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked., |