Gene name: | Adrb2(Adrb2r); |
Protein name: | Beta-2 adrenergic receptor; |
Alternative: | Beta-2 adrenoreceptor(Beta-2 adrenoceptor); |
Organism: | Rat (Rattus norvegicus). |
Sub Unit: | Binds SLC9A3R1 and GPRASP1. Interacts with ARRB1 and ARRB2. Interacts with SRC, USP20 and USP33. |
Function: | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. |
Subcellular Location: | Cell membrane Multi-pass membrane protein |
Sequence length: | 418 |
Sequence: | |
50: | MEPHGNDSDF | LLAPNGSRAP | GHDITQERDE | AWVVGMAILM | SVIVLAIVFG | |
100: | NVLVITAIAK | FERLQTVTNY | FITSLACADL | VMGLAVVPFG | ASHILMKMWN | |
150: | FGNFWCEFWT | SIDVLCVTAS | IETLCVIAVD | RYVAITSPFK | YQSLLTKNKA | |
200: | RVVILMVWIV | SGLTSFLPIQ | MHWYRATHKQ | AIDCYAKETC | CDFFTNQAYA | |
250: | IASSIVSFYV | PLVVMVFVYS | RVFQVAKRQL | QKIDKSEGRF | HAQNLSQVEQ | |
300: | DGRSGHGLRS | SSKFCLKEHK | ALKTLGIIMG | TFTLCWLPFF | IVNIVHVIRA | |
350: | NLIPKEVYIL | LNWLGYVNSA | FNPLIYCRSP | DFRIAFQELL | CLRRSSSKTY | |
400: | GNGYSSNSNG | RTDYTGEQSA | YQLGQEKENE | LLCEEAPGME | GFVNCQGTVP | |
418: | SLSIDSQGRN | CNTNDSPL |
3D Structure: | N/A |
UniGene: | Rn.10206 |
String: | P10608 |
SMR: | P10608 |
Pfam: | PF00001 |
Uniprot: | P10608 |