Gene name: | ADRB2; |
Protein name: | Beta-2 adrenergic receptor; |
Alternative: | Beta-2 adrenoreceptor(Beta-2 adrenoceptor); |
Organism: | Pig (Sus scrofa). |
Sub Unit: | Binds SLC9A3R1 and GPRASP1. Interacts with ARRB1 and ARRB2. Interacts with SRC, USP20 and USP33. |
Function: | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. |
Subcellular Location: | Cell membrane Multi-pass membrane protein |
Sequence length: | 418 |
Sequence: | |
50: | MGQPGNRSVF | LLAPNGSHAP | DQDVPQERDE | AWVVGMAIVM | SLIVLAIVFG | |
100: | NVLVITAIAK | FERLQTVTNY | FITSLACADL | VMGLAVVPFG | ASHILMKMWT | |
150: | FGSFWCEFWI | SIDVLCVTAS | IETLCVIAVD | RYLAITSPFK | YQCLLTKNKA | |
200: | RVVILMVWVV | SGLISFLPIK | MHWYQATHRE | ALNCYAEEAC | CDFFTNQPYA | |
250: | IASSIVSFYL | PLVVMVFVYS | RVFQVARRQL | QKIDKSEGRF | HAQNLSQAEQ | |
300: | DGRSGPGHRR | SSKFCLKEHK | ALKTLGIIMG | TFTLCWLPFF | IVNIVHGIHD | |
350: | NLIPKEVYIL | LNWVGYVNSA | FNPLIYCRSP | DFRMAFQELL | CLHRSSLKAY | |
400: | GNGCSSNSNG | RTDYTGEQSG | CYLGEEKDSE | RLCEDAPGPE | GCAHRQGTVP | |
418: | DDSTDSQGRN | CSTNDSML |
3D Structure: | N/A |
SMR: | Q28997 |
String: | Q28997 |
UniGene: | Ssc.16077 |
STRING: | 9823.ENSSSCP00000015357 |
KEGG: | ssc:397357 |
Pfam: | PF00001 |
Uniprot: | Q28997 |